Local and systemic immunity to influenza infections in ferrets

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Local and systemic immunity to influenza infections in ferrets.

To establish whether immunity to influenza infection in the ferret is local or systemic, two sites of challenge were utilized: the nose and the anatomically isolated tracheal pouch. Infection of either site did not spread to the other site, and challenge of either site resulted in seroconversion by 13 days. Simultaneous challenge of both sites 21 days after the primary infection revealed that p...

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Heterotypic immunity to influenza virus in ferrets operated against heterotypic influenza viruses but not heterologous viruses. Contrary to prior reports, the protection conferred lasted for at least 18 months. This type of immunity limited virus shedding but did not prevent infection. These results suggest that this phenomenon could play a role in determining the severity of infections caused ...

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Eyedrop Vaccination Induced Systemic and Mucosal Immunity against Influenza Virus in Ferrets

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1978

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.21.1.221-228.1978